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DMTs and Covid‐19 severity in MS: a pooled analysis from Italy and France

Authors :
Maria Pia Sormani
Marco Salvetti
Pierre Labauge
Irene Schiavetti
Helene Zephir
Luca Carmisciano
Caroline Bensa
Nicola De Rossi
Jean Pelletier
Cinzia Cordioli
Sandra Vukusic
Lucia Moiola
Philippe Kerschen
Marta Radaelli
Marie Théaudin
Paolo Immovilli
Olivier Casez
Marco Capobianco
Jonathan Ciron
Maria Trojano
Bruno Stankoff
Alain Créange
Gioacchino Tedeschi
Pierre Clavelou
Giancarlo Comi
Eric Thouvenot
Mario Alberto Battaglia
Thibault Moreau
Francesco Patti
Jérôme De Sèze
Celine Louapre
the Musc‐
the Covisep study groups
Source :
Annals of Clinical and Translational Neurology, Vol 8, Iss 8, Pp 1738-1744 (2021)
Publication Year :
2021
Publisher :
Wiley, 2021.

Abstract

Abstract We evaluated the effect of DMTs on Covid‐19 severity in patients with MS, with a pooled‐analysis of two large cohorts from Italy and France. The association of baseline characteristics and DMTs with Covid‐19 severity was assessed by multivariate ordinal‐logistic models and pooled by a fixed‐effect meta‐analysis. 1066 patients with MS from Italy and 721 from France were included. In the multivariate model, anti‐CD20 therapies were significantly associated (OR = 2.05, 95%CI = 1.39–3.02, p

Details

Language :
English
ISSN :
23289503
Volume :
8
Issue :
8
Database :
Directory of Open Access Journals
Journal :
Annals of Clinical and Translational Neurology
Publication Type :
Academic Journal
Accession number :
edsdoj.03cd08037d4f2191d0b6ce786e866a
Document Type :
article
Full Text :
https://doi.org/10.1002/acn3.51408