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Effect of S‐1 on blood levels of phenobarbital and phenytoin: A case report
- Source :
- Clinical Case Reports, Vol 9, Iss 3, Pp 1514-1517 (2021)
- Publication Year :
- 2021
- Publisher :
- Wiley, 2021.
-
Abstract
- Abstract Drug‐drug interaction of fluorinated pyrimidine anticancer agents with phenytoin is well known, but interaction with phenobarbital is limited. We describe a case showing increases in plasma phenobarbital as well as phenytoin concentrations during preoperative S‐1 (tegafur/gimeracil/oteracil) and radiation therapy for rectal cancer.
Details
- Language :
- English
- ISSN :
- 20500904
- Volume :
- 9
- Issue :
- 3
- Database :
- Directory of Open Access Journals
- Journal :
- Clinical Case Reports
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.0331a36dcae44749807520ab417b25a
- Document Type :
- article
- Full Text :
- https://doi.org/10.1002/ccr3.3813