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USP32 regulates late endosomal transport and recycling through deubiquitylation of Rab7
- Source :
- Nature Communications, Vol 10, Iss 1, Pp 1-18 (2019)
- Publication Year :
- 2019
- Publisher :
- Nature Portfolio, 2019.
-
Abstract
- Though ubiquitin is known to broadly influence endosomal trafficking, few ubiquitin-utilizing enzymes targeting endosomal regulators are known. Here, the authors find that the deubiquitylating enzyme (DUB) USP32 influences endosomal membrane dynamics by deubiquitinating Rab7.
- Subjects :
- Science
Subjects
Details
- Language :
- English
- ISSN :
- 20411723
- Volume :
- 10
- Issue :
- 1
- Database :
- Directory of Open Access Journals
- Journal :
- Nature Communications
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.03097ad9b5bc4f32abfc5298bf844d05
- Document Type :
- article
- Full Text :
- https://doi.org/10.1038/s41467-019-09437-x