Colistin-Resistant Acinetobacter baumannii as a cause of Neonatal Ventriculitis

Acinetobacter baumannii causes invasive paediatric infections, including bacteraemia and meningitis, but neonatal meningitis and ventriculitis is uncommon. The treatment of multidrug resistant (MDR) Acinetobacter infections often relies on colistin, a polymyxin antibiotic, as a last resort. Increased use of this drug has led to the emergence of colistin resistance. An unusual case of colistin-resistant Acinetobacter baumannii ventriculitis in a premature neonate managed with intraventricular colistin is described.