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Impact of high neutrophil‐to‐lymphocyte ratio on survival in hospitalized cancer patients with COVID‐19

Authors :
Fernando A. Díaz‐Couselo
Santiago Flagel
Carla Nicolini
Sebastián Halac
Natalia Manzano
Marina Aguirre
Juan Rébora
Sandra Valle
Laura Noro
Chirayu Mohindroo
Florencia McAllister
Marcelo Zylberman
Source :
Cancer Medicine, Vol 12, Iss 6, Pp 7164-7169 (2023)
Publication Year :
2023
Publisher :
Wiley, 2023.

Abstract

Abstract Neutrophil‐to‐lymphocyte ratio (NLR) has been studied as a prognostic factor for mortality in COVID‐19 patients. Our study aimed to evaluate the association between NLR at COVID‐19 diagnosis and survival during the following 90 days in hospitalized patients with solid cancer. Between May 2020 and June 2021, 120 patients were included in a retrospective cohort study. Univariable analysis showed patients with an NLR > 8.3 were associated with an increased risk of death (HR: 4.34; 95% CI: 1.74–10.84) compared to patients with NLR 8.30 independently correlated with increased mortality. In patients with solid malignancies with COVID‐19, an NLR > 8.3 is associated with an increased risk of death.

Details

Language :
English
ISSN :
20457634
Volume :
12
Issue :
6
Database :
Directory of Open Access Journals
Journal :
Cancer Medicine
Publication Type :
Academic Journal
Accession number :
edsdoj.0251b0dcce7b4233a5121a0c166a0d83
Document Type :
article
Full Text :
https://doi.org/10.1002/cam4.5426