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Normalizing and denoising protein expression data from droplet-based single cell profiling
- Source :
- Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
- Publication Year :
- 2022
- Publisher :
- Nature Portfolio, 2022.
-
Abstract
- Current single cell protein expression profiling approaches come with substantial measurement noise. Here the authors discover the sources of this noise and develop a denoising algorithm that improves data quality and downstream applications.
- Subjects :
- Science
Subjects
Details
- Language :
- English
- ISSN :
- 20411723
- Volume :
- 13
- Issue :
- 1
- Database :
- Directory of Open Access Journals
- Journal :
- Nature Communications
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.01e0db9ea26e48418ff9d13820efbeb6
- Document Type :
- article
- Full Text :
- https://doi.org/10.1038/s41467-022-29356-8