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Treatment approaches to patients with multiple sclerosis and coexisting autoimmune disorders
- Source :
- Therapeutic Advances in Neurological Disorders, Vol 14 (2021)
- Publication Year :
- 2021
- Publisher :
- SAGE Publishing, 2021.
-
Abstract
- The past decades have yielded major therapeutic advances in many autoimmune conditions – such as multiple sclerosis (MS) – and thus ushered in a new era of more targeted and increasingly potent immunotherapies. Yet this growing arsenal of therapeutic immune interventions has also rendered therapy much more challenging for the attending physician, especially when treating patients with more than one autoimmune condition. Importantly, some therapeutic strategies are either approved for several autoimmune disorders or may be repurposed for other conditions, therefore opening new curative possibilities in related fields. In this article, we especially focus on frequent and therapeutically relevant concomitant autoimmune conditions faced by neurologists when treating patients with MS, namely psoriasis, rheumatoid arthritis and inflammatory bowel diseases. We provide an overview of the available disease-modifying therapies, highlight possible contraindications, show pathophysiological overlaps and finally present which therapeutics can be utilized as a combinatory treatment, in order to ‘kill two birds with one stone’.
- Subjects :
- Neurology. Diseases of the nervous system
RC346-429
Subjects
Details
- Language :
- English
- ISSN :
- 17562864 and 52544222
- Volume :
- 14
- Database :
- Directory of Open Access Journals
- Journal :
- Therapeutic Advances in Neurological Disorders
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.0197de52544222925e1e9dcc249fe1
- Document Type :
- article
- Full Text :
- https://doi.org/10.1177/17562864211035542