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Ephedrae Herba in combination with herbal medicine (Zhizichi decoction and Phellodendri Cortex) for weight reduction: a case series

Authors :
Eunji Lee
Sang-Hoon Yoon
Hyunho Kim
Young Doo Kim
Jungtae Leem
Jinbong Park
Source :
Integrative Medicine Research, Vol 9, Iss 2, Pp 100408- (2020)
Publication Year :
2020
Publisher :
Elsevier, 2020.

Abstract

Backgrounds: Ephedrae Herba is widely used to treat obesity. There is a concern for adverse events (AEs) using it and we need to develop strategies to attenuate it without its effectiveness for weight-reducing potential. We investigated the effects of a combination of Ephedra Herba with Zhizichi decoction and Phellodendri Cortex (Anmyungambi (AMGB) decoction) in reducing the incidence of Ephedra Herba-related AEs. Methods: We performed a retrospective chart review from a clinical case series of patients visiting the Jaonmi Korean Medicine Clinic (Seoul, Korea). The inclusion criteria was patients who were prescribed AMGB decoction, (containing Ephedrae Herba, Phellodendri Cortex, and Zhizichi decoction [Gardeniae Fructus, and Glycine Semen Preparata] in different proportions) for weight reduction. Exclusion of Phellodendri Cortex in the original AMGB preparation was allowed; conventional medications, acupuncture, and dietary supplements were not allowed. The primary outcome was absolute weight loss at the end of treatment. Results: Twenty-seven patients (6 men and 21 women), aged 18–75 years (mean age, 42.6 ± 11.1 years) and the average treatment duration was 39.4 days. Absolute weight loss at the end of treatment was 4.49 ± 2.40 kg. Fifteen patients lost more than 5% weight (55.6%). Treatment >45 days resulted in significantly greater weight loss compared to treatment

Details

Language :
English
ISSN :
22134220
Volume :
9
Issue :
2
Database :
Directory of Open Access Journals
Journal :
Integrative Medicine Research
Publication Type :
Academic Journal
Accession number :
edsdoj.00a666b80524378ac0a084269da31cf
Document Type :
article
Full Text :
https://doi.org/10.1016/j.imr.2020.100408