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Male hypogonadism: 14‐year prospective outcome in 550 men with type 2 diabetes
- Source :
- Endocrinology, Diabetes & Metabolism, Vol 2, Iss 3, Pp n/a-n/a (2019)
- Publication Year :
- 2019
- Publisher :
- Wiley, 2019.
-
Abstract
- Summary Introduction Hypogonadism is more prevalent in men with type 2 diabetes (T2DM) (25%‐40%) than in men without T2DM. Hypogonadism has been associated with poorer glycaemic outcomes and increased cardiovascular morbidity/mortality. We report a 14‐year follow‐up study to evaluate the influence of baseline testosterone level on T2DM outcomes. Research design and methods A total of 550 men with T2DM underwent baseline total testosterone and dihydrotestosterone measurement by tandem mass spectrometry. Mean age of the men was 59.7 ± 12 (mean ± SD) years. Sex hormone‐binding globulin (SHBG) was measured and free testosterone estimated. Patients were followed up between 2002 and 2016. Mean follow‐up period was 12.2 ± 4 years using the Salford (UK) Integrated Health Records system. Results Mean baseline total testosterone was 13.7 ± 5.8 nmol/L, and mean free testosterone was 245.7 ± 88.0 pmol/L. Mean for low total testosterone (
Details
- Language :
- English
- ISSN :
- 23989238
- Volume :
- 2
- Issue :
- 3
- Database :
- Directory of Open Access Journals
- Journal :
- Endocrinology, Diabetes & Metabolism
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.0081f6e5b2494e079b256bb12681037a
- Document Type :
- article
- Full Text :
- https://doi.org/10.1002/edm2.64