Back to Search
Start Over
Inactivation of TGFβ receptors in stem cells drives cutaneous squamous cell carcinoma
- Source :
- Nature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
- Publication Year :
- 2016
- Publisher :
- Nature Portfolio, 2016.
-
Abstract
- Cutaneous squamous cell carcinomas is a growing problem but the driver genes causing this remain poorly defined. Here, the authors demonstrate that inactivating driver mutations in TGFBR1 and TGFBR2occur in vemurafenib-induced and sporadic cutaneous squamous cell carcinomas.
- Subjects :
- Science
Subjects
Details
- Language :
- English
- ISSN :
- 20411723
- Volume :
- 7
- Issue :
- 1
- Database :
- Directory of Open Access Journals
- Journal :
- Nature Communications
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.007e4295faa9467ba2f947c4d342dc0a
- Document Type :
- article
- Full Text :
- https://doi.org/10.1038/ncomms12493