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The Atr-Chek1 pathway inhibits axon regeneration in response to Piezo-dependent mechanosensation
- Source :
- Nature Communications, Vol 12, Iss 1, Pp 1-20 (2021)
- Publication Year :
- 2021
- Publisher :
- Nature Portfolio, 2021.
-
Abstract
- The Atr-Check1 pathway is involved in cell cycle and the DNA damage response. Here, the authors show that the Atr-Check1 pathway can inhibit axon regeneration in response to Piezo-mediated mechanosensation, affecting functional recovery.
- Subjects :
- Science
Subjects
Details
- Language :
- English
- ISSN :
- 20411723
- Volume :
- 12
- Issue :
- 1
- Database :
- Directory of Open Access Journals
- Journal :
- Nature Communications
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.005c24fb0ae4423db9855a4fda43b7ac
- Document Type :
- article
- Full Text :
- https://doi.org/10.1038/s41467-021-24131-7