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The Impact of Socioeconomic Factors on Kidney Transplantation: A Systematic Review of Low- and Middle-Income Countries

Authors :
Nguyen Xuong Duong
Minh Sam Thai
Ngoc Sinh Tran
Khac Chuan Hoang
Quy Thuan Chau
Xuan Thai Ngo
Trung Toan Duong
Tan Ho Trong Truong
Hanh Thi Tuyet Ngo
Dat Tien Nguyen
Khoa Quy
Tien Dat Hoang
David-Dan Nguyen
Narmina Khanmammadova Onder
Dinno Francis Mendiola
Anh Tuan Mai
Muhammed A. Moukhtar Hammad
Huy Gia Vuong
Ho Yee Tiong
Se Young Choi
Tuan Thanh Nguyen
Source :
Société Internationale d’Urologie Journal, Vol 5, Iss 5, Pp 349-360 (2024)
Publication Year :
2024
Publisher :
The Société Internationale d’Urologie (SIU), 2024.

Abstract

Kidney transplantation (KT) is a preferred treatment for end-stage renal disease (ESRD) because it offers better long-term survival and cost-effectiveness compared to dialysis. Significant global disparities persist in access to KT, particularly in low- and middle-income countries (LMICs). This study aims to assess the epidemiology and outcomes of KT in LMICs while examining the relationship between a country’s income level and its KT prevalence. A systematic review of the literature was conducted, with searches of PubMed, Scopus, and Web of Science from inception to 31 May 2024. Relevant articles reporting on the epidemiology and outcomes of KT or ESRD patients undergoing kidney replacement therapy (KRT) in LMICs were included. A total of 8054 articles were identified, with 972 articles selected for full-text screening after initial title and abstract review. Following full-text screening, 35 articles met the inclusion criteria. The data showed significant variation in KRT and KT prevalence across different geographical locations. Higher-income countries within LMICs tended to have higher KT prevalence rates. Barriers such as inadequate healthcare infrastructure, limited financial resources, and insufficient organ donation frameworks were identified as contributing factors to the low KT rates in these regions. The study highlights the disparities in KT access and prevalence in LMICs, underscoring the need for targeted interventions and international collaboration to address these gaps. Efforts to increase both living and deceased donor transplants, expand health system capacity, and incorporate KT in healthcare planning are needed to close this gap. Global partnerships spearheaded by organizations such as The Transplantation Society (TTS) and the International Society of Nephrology (ISN) are crucial for improving KT rates and outcomes in LMICs.

Details

Language :
English
ISSN :
25636499
Volume :
5
Issue :
5
Database :
Directory of Open Access Journals
Journal :
Société Internationale d’Urologie Journal
Publication Type :
Academic Journal
Accession number :
edsdoj.0046c32cd4e344e9aa948b701066fb86
Document Type :
article
Full Text :
https://doi.org/10.3390/siuj5050054