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Modeling SARS-CoV-2 and influenza infections and antiviral treatments in human lung epithelial tissue equivalents

Authors :
Hoda Zarkoob
Anna Allué-Guardia
Yu-Chi Chen
Andreu Garcia-Vilanova
Olive Jung
Steven Coon
Min Jae Song
Jun-Gyu Park
Fatai Oladunni
Jesse Miller
Yen-Ting Tung
Ivan Kosik
David Schultz
James Iben
Tianwei Li
Jiaqi Fu
Forbes D. Porter
Jonathan Yewdell
Luis Martinez-Sobrido
Sara Cherry
Jordi B. Torrelles
Marc Ferrer
Emily M. Lee
Source :
Communications Biology, Vol 5, Iss 1, Pp 1-17 (2022)
Publication Year :
2022
Publisher :
Nature Portfolio, 2022.

Abstract

Human alveolar and tracheobronchial epithelial air liquid interface (ALI) tissues are used as models to examine cellular responses to SARS-CoV-2 and influenza A virus infections and as antiviral drug screening assay platforms.

Subjects

Subjects :
Biology (General)
QH301-705.5

Details

Language :
English
ISSN :
23993642
Volume :
5
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Communications Biology
Publication Type :
Academic Journal
Accession number :
edsdoj.003ca60ed064430890c5954d0c4a6343
Document Type :
article
Full Text :
https://doi.org/10.1038/s42003-022-03753-7