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Short cationic peptides for gene delivery into cancer cells

Authors :
Cirillo, S.
Zhao, X.
Brown, S.
Publication Year :
2017
Publisher :
University of Sheffield, 2017.

Abstract

In this thesis, A6K, A9K, G(IIKK)3I-NH2, the fluorescently FITC-labelled A9K and G(IIKK)3I-NH2 amphiphilic cationic peptides have been intensively studied to evaluate their interactions with eukaryotic cell and in particular their selectivity towards cancer cells. A possible usage of these cationic peptides as delivery vectors of small nucleic acids molecules was also investigated.

Subjects

Subjects :
660

Details

Language :
English
Database :
British Library EThOS
Publication Type :
Dissertation/ Thesis
Accession number :
edsble.733596
Document Type :
Electronic Thesis or Dissertation