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The effect of antidepressant treatment on brain-derived neurotropic factor expression in the rat hippocampus
- Publication Year :
- 2004
- Publisher :
- De Montfort University, 2004.
-
Abstract
- Enhanced BDNF expression has been implicated in the mechanisms of action of antidepressant treatment. Previous findings have shown that chronic antidepressant drug treatment produces a ’bi-phasic effect’ on total BDNF gene expression, i.e. down-regulation at 4h and up-regulation at 24h. The earlier effect is common to acute administration, while the latter is unique to chronic treatment.
- Subjects :
- 616.85
Subjects
Details
- Language :
- English
- Database :
- British Library EThOS
- Publication Type :
- Dissertation/ Thesis
- Accession number :
- edsble.649953
- Document Type :
- Electronic Thesis or Dissertation