Nuclear events during infection of avian fibroblasts with influenza virus

The work presented in this thesis is an attempt to evaluate the Molecular mechanisms of both host and viral nucleic acid metabolism in the nucleus of avian fibroblasts infected with influenza virus. The first section describes the alteration of the processing of rRNA in the nucleus of virus infected cells. The second section describes the kinetics of virus adsorption at 4° and room temperature and the occurrence of micropinocytosis in CEF cells at 4°. The third section describes the movement of viral nucleic acid into the nucleus of infected cells, its association with the cellular DNA and the subsequent exit of the viral RNA from the nucleus.