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Rigorous derivation of a Hele-Shaw type model and its non-symmetric traveling wave solution

Authors :
Feng, Yu
He, Qingyou
Liu, Jian-Guo
Zhou, Zhennan
Publication Year :
2024

Abstract

In this paper, we consider a Hele-Shaw model that describes tumor growth subject to nutrient supply. This model was recently studied in \cite{feng2022tumor} via asymptotic analysis. Our contributions are twofold: Firstly, we provide a rigorous derivation of this Hele-Shaw model by taking the incompressible limit of the porous medium reaction-diffusion equation, which solidifies the mathematical foundations of the model. Secondly, from a bifurcation theory perspective, we prove the existence of non-symmetric traveling wave solutions to the model, which reflect the intrinsic boundary instability in tumor growth dynamics.<br />Comment: 23 pages, 2 figures

Details

Database :
arXiv
Publication Type :
Report
Accession number :
edsarx.2404.16353
Document Type :
Working Paper