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A branching model for intergenerational telomere length dynamics

Authors :
Benetos, Athanasios
Coudray, Olivier
Gégout-Petit, Anne
Lenôtre, Lionel
Toupance, Simon
Villemonais, Denis
Publication Year :
2023

Abstract

We build and study an individual based model of the telomere length's evolution in a population across multiple generations. This model is a continuous time typed branching process, where the type of an individual includes its gamete mean telomere length and its age. We study its Malthusian's behaviour and provide numerical simulations to understand the influence of biologically relevant parameters.

Details

Database :
arXiv
Publication Type :
Report
Accession number :
edsarx.2311.09678
Document Type :
Working Paper