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Model predictive control for the prescription of antithyroid agents

Authors :
Menzel, Maylin
Wolff, Tobias M.
Dietrich, Johannes W.
Müller, Matthias A.
Publication Year :
2023

Abstract

Although hyperthyroidism is a common disease, the pharmaceutical therapy is based on a trial-and-error approach. We extend a mathematical model of the pituitary-thyroid feedback loop such that the intake of one antithyroid agent, namely methimazole (MMI), can be considered and use a model predictive control (MPC) scheme to determine suitable dosages.<br />Comment: 2 pages

Details

Database :
arXiv
Publication Type :
Report
Accession number :
edsarx.2307.16690
Document Type :
Working Paper