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ATP Synthase: A Moonlighting Enzyme with Unprecedented Functions

Authors :
Vigneau, Jean-Nicolas
Fahimi, Peyman
Ebert, Maximilian
Cheng, Youji
Tannahill, Connor
Muir, Paul
Nguyen-Dang, Thanh-Tung
Matta, Cherif F.
Source :
Chem. Commun., 2022, 58, 2650-2653
Publication Year :
2021

Abstract

ATP synthase's intrinsic molecular electrostatic potential (MESP) adds constructively to, and hence reinforces, the chemiosmotic voltage. This ATP synthase voltage represents a new free energy term that appears to have been overlooked. This term is at least roughly equal in order of magnitude and opposite in sign to the energy needed to be dissipated as a Maxwell's demon (Landauer principle).<br />Comment: 4 pages, 3 figures, 1 table

Details

Database :
arXiv
Journal :
Chem. Commun., 2022, 58, 2650-2653
Publication Type :
Report
Accession number :
edsarx.2112.12874
Document Type :
Working Paper
Full Text :
https://doi.org/10.1039/D1CC06793A