Back to Search Start Over

Discontinuous epidemic transition due to limited testing

Authors :
Scarselli, Davide
Budanur, Nazmi Burak
Timme, Marc
Hof, Björn
Publication Year :
2020

Abstract

High impact epidemics constitute one of the largest threats humanity is facing in the 21st century. Testing, contact tracing and quarantining are critical in slowing down epidemic dynamics, but may prove insufficient for highly contagious diseases. In the absence of pharmaceutical interventions, physical distancing measures remain as the last resort to avoid a widespread outbreak. Here we show that such combined countermeasures drastically change the rules of the epidemic transition if testing capacities are limited: Instead of continuous the response to countermeasures becomes discontinuous and rather than following the conventional exponential growth, the outbreak accelerates and scales super-exponentially during an intermediate period. As a consequence, containment measures either suffice to stop the outbreak at low total case numbers or fail catastrophically if marginally too weak, thus implying large uncertainties in reliably estimating overall epidemic dynamics, both during initial phases and during second wave scenarios.

Details

Database :
arXiv
Publication Type :
Report
Accession number :
edsarx.2006.08005
Document Type :
Working Paper
Full Text :
https://doi.org/10.1038/s41467-021-22725-9