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A minimal HIV-AIDS infection model with general incidence rate and application to Morocco data

Authors :
Lotfi, El Mehdi
Mahrouf, Marouane
Maziane, Mehdi
Silva, Cristiana J.
Torres, Delfim F. M.
Yousfi, Noura
Source :
Stat. Optim. Inf. Comput. 7 (2019), no. 3, 588--603
Publication Year :
2018

Abstract

We study the global dynamics of a SICA infection model with general incidence rate. The proposed model is calibrated with cumulative cases of infection by HIV-AIDS in Morocco from 1986 to 2015. We first prove that our model is biologically and mathematically well-posed. Stability analysis of different steady states is performed and threshold parameters are identified where the model exhibits clearance of infection or maintenance of a chronic infection. Furthermore, we examine the robustness of the model to some parameter values by examining the sensitivity of the basic reproduction number. Finally, using numerical simulations with real data from Morocco, we show that the model predicts well such reality.<br />Comment: This is a preprint of a paper whose final and definite form is with 'Statistics Opt. Inform. Comput.', Vol. 7, No 2 (2019). See [http://www.IAPress.org]. Submitted 16/Sept/2018; Revised 10 & 15/Dec/2018; Accepted 15/Dec/2018

Details

Database :
arXiv
Journal :
Stat. Optim. Inf. Comput. 7 (2019), no. 3, 588--603
Publication Type :
Report
Accession number :
edsarx.1812.06965
Document Type :
Working Paper
Full Text :
https://doi.org/10.19139/soic-2310-5070-834