Back to Search
Start Over
Mathematics for cryo-electron microscopy
- Publication Year :
- 2018
-
Abstract
- Single-particle cryo-electron microscopy (cryo-EM) has recently joined X-ray crystallography and NMR spectroscopy as a high-resolution structural method for biological macromolecules. Cryo-EM was selected by Nature Methods as Method of the Year 2015, large scale investments in cryo-EM facilities are being made all over the world, and the Nobel Prize in Chemistry 2017 was awarded to Jacques Dubochet, Joachim Frank and Richard Henderson "for developing cryo-electron microscopy for the high-resolution structure determination of biomolecules in solution". This paper focuses on the mathematical principles underlying existing algorithms for structure determination using single particle cryo-EM.<br />Comment: Proceedings of the International Congress of Mathematicians 2018
Details
- Database :
- arXiv
- Publication Type :
- Report
- Accession number :
- edsarx.1803.06714
- Document Type :
- Working Paper