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Nanodiamonds with silicon vacancy defects for non-toxic photostable fluorescent labeling of neural precursor cells
- Publication Year :
- 2013
-
Abstract
- Nanodiamonds (NDs) containing silicon vacancy (SiV) defects were evaluated as a potential biomarker for the labeling and fluorescent imaging of neural precursor cells (NPCs). SiV-containing NDs were synthesized using chemical vapor deposition and silicon ion implantation. Spectrally, SiV-containing NDs exhibited extremely stable fluorescence and narrow bandwidth emission with an excellent signal to noise ratio exceeding that of NDs containing nitrogen-vacancy (NV) centers. NPCs labeled with NDs exhibited normal cell viability and proliferative properties consistent with biocompatibility. We conclude that SiVcontaining NDs are a promising biomedical research tool for cellular labeling and optical imaging in stem cell research.<br />Comment: The paper was accepted for publication in Optics letters
Details
- Database :
- arXiv
- Publication Type :
- Report
- Accession number :
- edsarx.1309.5179
- Document Type :
- Working Paper
- Full Text :
- https://doi.org/10.1364/OL.38.004170