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New alphabet-dependent morphological transition in a random RNA alignment

Authors :
Valba, O. V.
Tamm, M. V.
Nechaev, S. K.
Publication Year :
2011

Abstract

We study the fraction $f$ of nucleotides involved in the formation of a cactus--like secondary structure of random heteropolymer RNA--like molecules. In the low--temperature limit we study this fraction as a function of the number $c$ of different nucleotide species. We show, that with changing $c$, the secondary structures of random RNAs undergo a morphological transition: $f(c)\to 1$ for $c \le c_{\rm cr}$ as the chain length $n$ goes to infinity, signaling the formation of a virtually "perfect" gapless secondary structure; while $f(c)<1$ for $c>c_{\rm cr}$, what means that a non-perfect structure with gaps is formed. The strict upper and lower bounds $2 \le c_{\rm cr} \le 4$ are proven, and the numerical evidence for $c_{\rm cr}$ is presented. The relevance of the transition from the evolutional point of view is discussed.<br />Comment: 4 pages, 3 figures (title is changed, text is essentially reworked), accepted in PRL

Details

Database :
arXiv
Publication Type :
Report
Accession number :
edsarx.1109.5410
Document Type :
Working Paper
Full Text :
https://doi.org/10.1103/PhysRevLett.109.018102