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Vector Competence to Zika Virus Changes Depending on the Manaus's Region Origin of the Aedes aegypti: A Study of an Endemic Brazilian Amazonian City
- Authors :
- Paz, Andréia da Costa
Chaves, Bárbara Aparecida
Godoy, Raquel Soares Maia
Coelho, Deilane Ferreira
Júnior, Ademir Bentes Vieira
Alencar, Rodrigo Maciel
Alcântara, João Arthur
Felix, Luiza dos Santos
Oliveira, Cinthia Catharina Azevedo
Monteiro, Wuelton Marcelo
Lacerda, Marcus Vinicius Guimarães
Secundino, Nágila Francinete Costa
Pimenta, Paulo Filemon Paolucci - Publication Year :
- 2022
- Publisher :
- Preprints, 2022.
-
Abstract
- Zika virus (ZIKV) is transmitted to humans by the infectious bite of mosquitoes like Aedes aegypti. After a viremic blood meal, the virus must infect the midgut, disseminate to tissues, and reach the salivary gland to be transmitted to a vertebrate host. Many factors influence the mosquito’s ability to become infected and transmit viruses, such as the mosquito’s genetic diversity, intrinsic antiviral barriers, and midgut microbiota. This study evaluated the patterns of ZIKV infection in Ae. aegypti field populations of a city. The infection rate, disseminated infection rate, viral transmission rate, and transmission efficiency were measured by quantitative PCR at 14 days post-infection. The results showed that all Ae. aegypti populations had individuals susceptible to ZIKV infection and able to transmit the virus. The infection parameters showed the city’s geographical area of origin of the Ae. aegypti influences their vector competence for ZIKV transmission.
- Subjects :
- virology
Subjects
Details
- Language :
- English
- Database :
- OpenAIRE
- Accession number :
- edsair.sharePrprorg..6aa5da6c6a7972956038f79cce69d0b3