Carotid plaque volume in patients undergoing carotid endarterectomy

Authors :: Ball, S.
Rogers, S.
Kanesalingam, K.
Taylor, R.
Katsogridakis, E.
McCollum, C.
Source :: The British Journal of Surgery, Ball, S, Rogers, S, Kanesalingam, K, Taylor, R L, Katsogridakis, E & Mccollum, C 2018, ' Carotid plaque volume in patients undergoing carotid endarterectomy ', British Journal of Surgery . https://doi.org/10.1002/bjs.10670, British Journal of Surgery
Publication Year :: 2018
Publisher :: John Wiley & Sons, Ltd, 2018.
Abstract: Background The main indication for carotid endarterectomy (CEA) is severity of carotid artery stenosis, even though most strokes in carotid disease are embolic. The relationship between carotid plaque volume (CPV) and symptoms of cerebral ischaemia, and the measurement of CPV by minimally invasive tomographic ultrasound imaging, were investigated. Methods The volume of the endarterectomy specimen was measured using a validated saline suspension technique in patients undergoing CEA. Time from last symptom and severity of stenosis measured by duplex ultrasonography were recorded. Middle cerebral artery emboli were counted using transcranial Doppler imaging (TCD) in a subset of patients. Results Some 339 patients were included, 270 with symptomatic and 69 with asymptomatic carotid stenosis. Mean(s.d.) CPV was higher in symptomatic than in asymptomatic patients (0·97(0·43) versus 0.74(0·41) cm3; P<br />Potential indication for treatment