Non inherited hemoglobin anomalies

A number of genetic or acquired conditions in which hemoglobin anomalies occur without detectable modifications of globin genes are reviewed. They include increased fetal hemoglobin (alpha 2 gamma 2), variations in hemoglobin A2 concentration, the presence of Hb H (beta 4), Bart's Hb (gamma 4), Hb Köelliker, glycosylated, carbamylated and acetylated hemoglobins.