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Target highlights in CASP13: Experimental target structures through the eyes of their authors

Authors :
Lepore, Rosalba
Kryshtafovych, Andriy
Alahuhta, Markus
Veraszto, Harshul A.
Bomble, Yannick J.
Bufton, Joshua C.
Bullock, Alex N.
Caba, Cody
Cao, Hongnan
Davies, Owen R.
Desfosses, Ambroise
Dunne, Matthew
Fidelis, Krzysztof
Goulding, Celia W.
Gurusaran, Manickam
Gutsche, Irina
Harding, Christopher J.
Hartmann, Marcus D.
Hayes, Christopher S.
Joachimiak, Andrzej
Leiman, Petr G.
Loppnau, Peter
Lovering, Andrew L.
Lunin, Vladimir V.
Michalska, Karolina
Mir‐Sanchis, Ignacio
Mitra, AK
Moult, John
Phillips Jr, George N.
Pinkas, Daniel M.
Rice, Phoebe A.
Tong, Yufeng
Topf, Maya
Walton, Jonathan D.
Schwede, Torsten
Department of Physics [Roma La Sapienza]
Università degli Studi di Roma 'La Sapienza' = Sapienza University [Rome]
Genome Center [UC Davis]
University of California [Davis] (UC Davis)
University of California-University of California
University of Bristol [Bristol]
Institut de biologie structurale (IBS - UMR 5075 )
Université Grenoble Alpes [2016-2019] (UGA [2016-2019])-Institut de Recherche Interdisciplinaire de Grenoble (IRIG)
Direction de Recherche Fondamentale (CEA) (DRF (CEA))
Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Direction de Recherche Fondamentale (CEA) (DRF (CEA))
Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Centre National de la Recherche Scientifique (CNRS)
Dept Mol Cellular & Dev Biol
University of California [Santa Barbara] (UCSB)
Structural Biology Center
Biosciences Division
University of Toronto
Southmead Hospital
Institute of Mathematical Problems in Biology (IMPB RAS)
Russian Academy of Sciences [Moscow] (RAS)
School of Biological Sciences [Auckland]
University of Auckland [Auckland]
Department of Cell Biology and Molecular Genetics
University of Maryland [College Park]
University of Maryland System-University of Maryland System
Department of Biological Sciences
Institute of Structural and Molecular Biology (ISMB)-Birkbeck College [University of London]
Biozentrum [Basel, Suisse]
University of Basel (Unibas)
Dipartimento di Fisica [Roma La Sapienza]
Università degli Studi di Roma 'La Sapienza' = Sapienza University [Rome] (UNIROMA)
University of California (UC)-University of California (UC)
Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes [2016-2019] (UGA [2016-2019])-Institut de Recherche Interdisciplinaire de Grenoble (IRIG)
Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)
University of California [Santa Barbara] (UC Santa Barbara)
Birkbeck College [University of London]-Institute of Structural and Molecular Biology (ISMB)
Source :
Proteins-Structure, Function and Bioinformatics, Proteins-Structure, Function and Bioinformatics, Wiley, 2019, 87 (12), pp.1037-1057. ⟨10.1002/prot.25805⟩, Proteins-Structure, Function and Bioinformatics, 2019, 87 (12), pp.1037-1057. ⟨10.1002/prot.25805⟩, Lepore, R, Kryshtafovych, A, Alahuhta, M, Veraszto, H A, Bomble, Y J, Bufton, J C, Bullock, A N, Caba, C, Cao, H, Davies, O R, Desfosses, A, Dunne, M, Fidelis, K, Goulding, C W, Gurusaran, M, Gutsche, I, Harding, C J, Hartmann, M D, Hayes, C S, Joachimiak, A, Leiman, P G, Loppnau, P, Lovering, A L, Lunin, V V, Michalska, K, Mir-Sanchis, I, Mitra, A K, Moult, J, Phillips, G N, Pinkas, D M, Rice, P A, Tong, Y, Topf, M, Walton, J D & Schwede, T 2019, ' Target highlights in CASP13 : Experimental target structures through the eyes of their authors ', Proteins: Structure, Function and Bioinformatics, vol. 87, no. 12, pp. 1037-1057 . https://doi.org/10.1002/prot.25805, Proteins, Lepore, R, Kryshtafovych, A, Alahuhta, M, Veraszto, H, Bomble, Y, Bufton, J C, Bullock, A N, Caba, C, Coa, H, Davies, O, Desfosses, A, Dunne, M, Fidelis, K, Goulding, C, Gurusanran, M, Gutsche, I, Harding, C, Hartmann, M, Hayes, C S, Joachimiak, A, Leiman, P, Loppnau, P, Lovering, A, Lunin, V Y, Michalska, K, Mir-Sanchis, I, Mitra, A, Moult, J, Philips, G, Pinkas, D M, Rice, P, Tong, Y, Topf, M, Walton, J & Schwede, T 2019, ' Target highlights in CASP13 : experimental target structures through the eyes of their authors ', Proteins: Structure, Function, and Bioinformatics . https://doi.org/10.1002/prot.25805, Proteins: Structure, Function and Bioinformatics, 87 (S 12)
Publication Year :
2019
Publisher :
HAL CCSD, 2019.

Abstract

International audience; The functional and biological significance of selected CASP13 targets are described by the authors of the structures. The structural biologists discuss the most interesting structural features of the target proteins and assess whether these features were correctly reproduced in the predictions submitted to the CASP13 experiment.

Details

Language :
English
ISSN :
08873585 and 10970134
Database :
OpenAIRE
Journal :
Proteins-Structure, Function and Bioinformatics, Proteins-Structure, Function and Bioinformatics, Wiley, 2019, 87 (12), pp.1037-1057. ⟨10.1002/prot.25805⟩, Proteins-Structure, Function and Bioinformatics, 2019, 87 (12), pp.1037-1057. ⟨10.1002/prot.25805⟩, Lepore, R, Kryshtafovych, A, Alahuhta, M, Veraszto, H A, Bomble, Y J, Bufton, J C, Bullock, A N, Caba, C, Cao, H, Davies, O R, Desfosses, A, Dunne, M, Fidelis, K, Goulding, C W, Gurusaran, M, Gutsche, I, Harding, C J, Hartmann, M D, Hayes, C S, Joachimiak, A, Leiman, P G, Loppnau, P, Lovering, A L, Lunin, V V, Michalska, K, Mir-Sanchis, I, Mitra, A K, Moult, J, Phillips, G N, Pinkas, D M, Rice, P A, Tong, Y, Topf, M, Walton, J D & Schwede, T 2019, ' Target highlights in CASP13 : Experimental target structures through the eyes of their authors ', Proteins: Structure, Function and Bioinformatics, vol. 87, no. 12, pp. 1037-1057 . https://doi.org/10.1002/prot.25805, Proteins, Lepore, R, Kryshtafovych, A, Alahuhta, M, Veraszto, H, Bomble, Y, Bufton, J C, Bullock, A N, Caba, C, Coa, H, Davies, O, Desfosses, A, Dunne, M, Fidelis, K, Goulding, C, Gurusanran, M, Gutsche, I, Harding, C, Hartmann, M, Hayes, C S, Joachimiak, A, Leiman, P, Loppnau, P, Lovering, A, Lunin, V Y, Michalska, K, Mir-Sanchis, I, Mitra, A, Moult, J, Philips, G, Pinkas, D M, Rice, P, Tong, Y, Topf, M, Walton, J & Schwede, T 2019, ' Target highlights in CASP13 : experimental target structures through the eyes of their authors ', Proteins: Structure, Function, and Bioinformatics . https://doi.org/10.1002/prot.25805, Proteins: Structure, Function and Bioinformatics, 87 (S 12)
Accession number :
edsair.pmid.dedup....ea58a962ee07463c99150fb018a2734d
Full Text :
https://doi.org/10.1002/prot.25805⟩