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Prevalence of extended spectrum beta lactamase and AmpC beta lactamase producers among Escherichia coli isolates in a tertiary care hospital in Jaipur
- Source :
- Indian Journal of Pathology and Microbiology, Vol 51, Iss 3, Pp 367-369 (2008)
- Publication Year :
- 2008
-
Abstract
- Resistance to broad spectrum β lactams, mediated by extended spectrum beta lactamase (ESβL) and AmpC βL enzymes is an increasing problem worldwide. Presence of these in clinical infections can result in treatment failure if one of the second or third generation cephalosporins is used. Therefore, it is recommended that any ESβL-producing organism according to the National Committee for Clinical Laboratory Standards (NCCLS) criteria can be reported as resistant to all extended spectrum β lactam antibiotics regardless of the susceptibility test results. In this study, a total of 250 Escherichia coli (E. coli) isolates were subjected to Double disc test and AmpC disc test for the detection of ESβL- and AmpC βL-producing strains, respectively. Prevalence of ESβL- and AmpC βL-producing strains among E. coli isolates, over a 3-month-period in the hospital-based population of Jaipur, was 64.80% (162/250). AmpC βL producers were 24.00% (60/250) and co-existence of ESβL and AmpC βL was detected in 8.00% (20/250) of the isolates.
- Subjects :
- extended spectrum beta lactamase
lcsh:QR1-502
India
Microbial Sensitivity Tests
biochemical phenomena, metabolism, and nutrition
bacterial infections and mycoses
beta-Lactams
AmpC βL
lcsh:Microbiology
Hospitals
beta-Lactam Resistance
beta-Lactamases
Anti-Bacterial Agents
beta lactam
polycyclic compounds
lcsh:Pathology
Escherichia coli
Humans
Escherichia coli Infections
lcsh:RB1-214
Subjects
Details
- ISSN :
- 03774929
- Volume :
- 51
- Issue :
- 3
- Database :
- OpenAIRE
- Journal :
- Indian journal of pathologymicrobiology
- Accession number :
- edsair.pmid.dedup....d775dcf7e3a58807caf376ab482d5d24