Synthesis and antiinflammatory activity of some N-(5-substituted indole-3-ylglyoxyl)amine derivatives

The synthesis of some amidic derivatives, obtained by condensation of various 5-substituted indoleglyoxylchlorides with physiologically important amines as tyramine, tryptamine and 5-aminouracil, is described. The preparation of one glycolyl derivative is also reported. Study of analgesic and antiinflammatory properties has shown only a feeble activity of these compounds.