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Model Description Language (MDL): A Standard for Modeling and Simulation

Authors :
Smith, MK
Moodie, SL
Bizzotto, R
E, Blaudez.
Borella, E
Carrara, L
Chan, P
Chenel, M
Comets, E
Gieschke, R
Harling, K
Harnisch, L
Hartung, N
Hooker, AC
Karlsson, MO
Kaye, R
Kloft, C
Kokash, N
Lavielle, M
Lestini, G
Magni, P
Mari, A
Mentré, F
Muselle, C
Nordgren, R
Nyberg, HB
Parra-Guillén, ZP
Pasotti, L
Rode-Kristensen, N
Sardu, ML
Smith, GR
Swat, MJ
Terranova, N
Yngman, G
Yvon, F
Holford, N
consortium, DDMoRe
Source :
CPT: Pharmacometrics & Systems Pharmacology
Publication Year :
2017

Abstract

Recent work on Model Informed Drug Discovery and Development (MID3) has noted the need for clarity in model description used in quantitative disciplines such as pharmacology and statistics. 1-3 Currently, models are encoded in a variety of computer languages and are shared through publications that rarely include original code and generally lack reproducibility. The DDMoRe Model Description Language (MDL) has been developed primarily as a language standard to facilitate sharing knowledge and understanding of models.

Details

ISSN :
21638306
Volume :
6
Issue :
10
Database :
OpenAIRE
Journal :
CPT: pharmacometricssystems pharmacology
Accession number :
edsair.pmid.dedup....c1e760f1b513fd790d02856dd2db557e