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[In vitro testing for drug resistance and drug sensitivity in clinical oncology]
- Source :
- Europe PubMed Central
- Publication Year :
- 2001
-
Abstract
- In vitro methods for testing chemosensitivity and chemoresistance can contribute considerably to more individual chemotherapy of a given patient. Different tests which reflect with a different reliability and specificity the probable ineffectiveness of chemotherapy can be divided into several categories: 1. Indirect tests associated with general biological activity of the tumour. 2. Tests based on the specific relationship to a certain cytostatic. 3. Examination of hormonal receptors. 4. Direct tests based on testing of the sensitivity or resistance of a tumour to different cytostatics in primocultures or stabilized cultures. The submitted review presents information on different methods.
Details
- Language :
- Czech
- ISSN :
- 0042773X
- Volume :
- 47
- Issue :
- 9
- Database :
- OpenAIRE
- Journal :
- Vnitrni lekarstvi
- Accession number :
- edsair.pmid.dedup....bc9e296c0fc06f27733132542182161e