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A multicenter, randomized, double-blind, placebo-controlled trial of adjuvant methotrexate treatment for giant cell arteritis
- Source :
- Arthritis and rheumatism. 46(5)
- Publication Year :
- 2002
-
Abstract
- OBJECTIVE: To evaluate treatment with methotrexate (MTX) in patients with newly diagnosed giant cell arteritis (GCA) to determine if MTX reduces GCA relapses and cumulative corticosteroid (CS) requirements and diminishes disease- and treatment-related morbidity. METHODS: This was a multicenter, randomized, double-blind study. Over 4 years, 16 centers from the International Network for the Study of Systemic Vasculitides enrolled patients with unequivocal GCA. The initial treatment was 1 mg/kg/day (
Details
- ISSN :
- 00043591
- Volume :
- 46
- Issue :
- 5
- Database :
- OpenAIRE
- Journal :
- Arthritis and rheumatism
- Accession number :
- edsair.pmid.dedup....ba75d2608ec9c34218290f075377ec8e