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Ten‐year retrospective review (2003‐2013) of 56 inpatient admissions to stabilize elevated phenylalanine levels

Authors :
Anne, Clark
Christine, Merrigan
Ellen, Crushell
Joanne, Hughes
Ina, Knerr
Ardeshir A, Monavari
Eileen, Treacy
Aoife, Coughlan
Source :
JIMD Reports
Publication Year :
2019
Publisher :
John Wiley & Sons, Inc., 2019.

Abstract

Phenylketonuria (PKU) is an inherited metabolic disorder affecting phenylalanine metabolism. The Irish incidence is 1:4500. Currently, there are 500 patients under the care of the National Centre for Inherited Metabolic Disorders in Temple Street Children's University Hospital. Current practice is to admit PKU patients with phenylalanine (phe) levels that are consistently out of range despite an intensive multidisciplinary team input on an outpatient basis. The aim of this study was to evaluate changes in phe levels pre, during, and post admissions and to examine if there was a sustained impact post discharge. Fifty‐six patients were admitted between January 2003 and December 2013. Patients were all

Details

Language :
English
ISSN :
21928312 and 21928304
Volume :
46
Issue :
1
Database :
OpenAIRE
Journal :
JIMD Reports
Accession number :
edsair.pmid.dedup....82219da0546b1d80bc3935fbb066078d