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[Stevens-Johnson syndrome followed by Gougerot-Sjögren syndrome]
- Source :
- Europe PubMed Central
- Publication Year :
- 2001
-
Abstract
- Sicca syndrome after Stevens-Johnson syndrome is classically described. However, to our knowledge, authentic Sjögren's syndrome following epidermal necrolysis has not been described previously.A 36-year-old woman with Steven-Johnson syndrome developed transient hepatitis and a persistent sicca syndrome. Fourteen years later an authentic Sjögren's syndrome was identified with presence of antinuclear and anti-SSA antibodies and lymphocytes infiltration of the accessory salivary glands, i.e. grade IV disease in the Chisholm classification.The initial mucosal destruction observed in our patients may have laid the ground for Sjögren's syndrome via abnormal antigen presentation in a predisposed dysimmune context.
Details
- Language :
- French
- ISSN :
- 07554982
- Volume :
- 30
- Issue :
- 11
- Database :
- OpenAIRE
- Journal :
- Presse medicale (Paris, France : 1983)
- Accession number :
- edsair.pmid.dedup....7dc656599f7df9ac55cc9f2f0c9a58cc