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K-edge subtraction imaging for coronary angiography with a compact synchrotron X-ray source
- Source :
- PLoS ONE, PLoS ONE, Vol 13, Iss 12, p e0208446 (2018)
- Publication Year :
- 2018
- Publisher :
- Public Library of Science, 2018.
-
Abstract
- About one third of all deaths worldwide can be traced back to cardiovascular diseases. An interventional radiology procedure for their diagnosis is Digital Subtraction Angiography (DSA). An alternative to DSA is K-Edge subtraction (KES) imaging, which has been shown to be advantageous for moving organs and eliminating image artifacts caused by patient movement. As highly brilliant, monochromatic X-rays are required for this method, it has been limited to synchrotron facilities so far, restraining the feasibility in clinical routine. Compact synchrotron X-ray sources based on inverse Compton scattering, which have been evolving substantially over the past decade, provide X-rays with sufficient brilliance that meet spatial and financial requirements affordable in laboratory settings or for university hospitals. In this work, we demonstrate a first proof-of-principle K-edge subtraction imaging experiment using the Munich Compact Light Source (MuCLS), the first user-dedicated installation of a compact synchrotron X-ray source worldwide. It is shown experimentally that the technique of KES increases the visibility of small blood vessels overlaid by bone structures.
- Subjects :
- Imaging Techniques
Swine
Science
Equipment
Cardiovascular Medicine
Signal-To-Noise Ratio
Research and Analysis Methods
Coronary Angiography
Diagnostic Radiology
Diagnostic Medicine
Medicine and Health Sciences
Image Processing, Computer-Assisted
Animals
Cardiovascular Imaging
Particle Physics
Photons
Phantoms, Imaging
Radiology and Imaging
Physics
X-Rays
Angiography
Rib Cage
Biology and Life Sciences
Angiography, Digital Subtraction
Heart
Equipment Design
Bone Imaging
X-Ray Radiography
Radiographic Image Enhancement
Chemistry
Physical Sciences
Cardiovascular Anatomy
Medicine
Engineering and Technology
Blood Vessels
Feasibility Studies
Particle Accelerators
Anatomy
Synchrotrons
Elementary Particles
Research Article
Chemical Elements
Iodine
Aluminum
Subjects
Details
- Language :
- English
- ISSN :
- 19326203
- Volume :
- 13
- Issue :
- 12
- Database :
- OpenAIRE
- Journal :
- PLoS ONE
- Accession number :
- edsair.pmid.dedup....72fcecd930b693f0e3ead9b79e2ae232