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Dataset on structure, stability and myocardial effects of a new hybrid aspirin containing nitrogen monoxide-releasing molsidomine moiety

Authors :
Kitti Szőke
Attila Czompa
István Lekli
Péter Szabados-Fürjesi
Mihály Herczeg
Magdolna Csávás
Anikó Borbás
Pál Herczegh
Árpád Tósaki
Source :
Data in Brief, Vol 25, Iss, Pp-(2019)
Publication Year :
2019

Abstract

Herein 1H and 13C NMR spectra of ERJ-500, a new hybrid aspirin derivative, covalently conjugated to nitrogen monoxide donor linsidomine are presented as well as NMR spectra of its synthetic intermediate compounds. HPLC-MS measurements data are also included, demonstrating the stability of the linsidomine-aspirin hybrid in oxidation reactions. This data article also concerns miscellaneous myocardial parameters of isolated rat hearts as a complementation of the tables shown in the paper entitled “A new, vasoactive hybrid aspirin containing nitrogen monoxide-releasing molsidomine moiety” Szoke et al., 2019. Column tables represent data of aorta flow, aortic pressure, derivated aortic pressure and cardiac output. Keywords: ERJ-500, Hybrid aspirin, Molsidomine

Details

Language :
English
Database :
OpenAIRE
Journal :
Data in Brief, Vol 25, Iss, Pp-(2019)
Accession number :
edsair.pmid.dedup....5fa56f2aafbfe509698d94422781dc11