Back to Search
Start Over
Evaluation of 3D blood flow patterns and wall shear stress in the normal and dilated thoracic aorta using flow-sensitive 4D CMR
- Source :
- Journal of Cardiovascular Magnetic Resonance, Journal of Cardiovascular Magnetic Resonance, Vol 14, Iss 1, p 84 (2012)
- Publisher :
- Springer Nature
-
Abstract
- Background The purpose of this study was to investigate 3D flow patterns and vessel wall parameters in patients with dilated ascending aorta, age-matched subjects, and healthy volunteers. Methods Thoracic time-resolved 3D phase contrast CMR with 3-directional velocity encoding was applied to 33 patients with dilated ascending aorta (diameter ≥40 mm, age=60±16 years), 15 age-matched normal controls (diameter ≤37 mm, age=68±7.5 years) and 15 young healthy volunteers (diameter ≤30 mm, age=23±2 years). 3D blood flow was visualized and flow patterns were graded regarding presence of supra-physiologic-helix and vortex flow using a semi-quantitative 3-point grading scale. Blood flow velocities, regional wall shear stress (WSS), and oscillatory shear index (OSI) were quantified. Results Incidence and strength of supra-physiologic-helix and vortex flow in the ascending aorta (AAo) was significantly higher in patients with dilated AAo (16/33 and 31/33, grade 0.9±1.0 and 1.5±0.6) than in controls (2/15 and 7/15, grade 0.2 ± 0.6 and 0.6 ± 0.7, PPPPPPPP Conclusions Increase in AAo diameter is significantly correlated with the presence and strength of supra-physiologic-helix and vortex formation in the AAo, as well with decrease in systolic WSS and increase in OSI.
- Subjects :
- Adult
Male
Medicine(all)
lcsh:Diseases of the circulatory (Cardiovascular) system
Time Factors
Aortic Aneurysm, Thoracic
Research
4D flow
Aorta, Thoracic
Middle Aged
Aneurysm of the ascending aorta
Imaging, Three-Dimensional
lcsh:RC666-701
Predictive Value of Tests
Regional Blood Flow
Image Interpretation, Computer-Assisted
Humans
Flow quantification
Female
Stress, Mechanical
Blood Flow Velocity
Magnetic Resonance Angiography
Aged
Dilatation, Pathologic
Retrospective Studies
Subjects
Details
- Language :
- English
- ISSN :
- 1532429X
- Volume :
- 14
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- Journal of Cardiovascular Magnetic Resonance
- Accession number :
- edsair.pmid.dedup....4a1120809d9593943d99449d12b9c891
- Full Text :
- https://doi.org/10.1186/1532-429x-14-84