MicroRNA Landscape in Alzheimer's Disease

Authors :: Cogoni C
Ruberti F
Barbato C
Source :: CNS & neurological disorders. Drug targets 14 (2015): 168–175. doi:10.2174/1871527314666150116123305, info:cnr-pdr/source/autori:Cogoni C, Ruberti F, Barbato C/titolo:MicroRNA Landscape in Alzheimer's Disease./doi:10.2174%2F1871527314666150116123305/rivista:CNS & neurological disorders. Drug targets/anno:2015/pagina_da:168/pagina_a:175/intervallo_pagine:168–175/volume:14
Publication Year :: 2015
Abstract: Individual microRNAs and/or microRNA signatures were associated with AD. We report here the recent advances brought to the identification of microRNA changes in Alzheimer's disease (AD) brain and their biological function in the molecular pathways associated with the disease. This field represents a fertile route to understand the pathogenic mechanisms underlying Alzheimer's disease. In addition we review recent studies aimed to discover promising biomarkers for AD diagnosis by microRNA expression profiles of biofluids from AD patients.

Subjects :: MicroRNAs
gene silencing
microRNA
Alzheimer Disease
Alzheimer
Brain
Humans
microRNA, Alzheimer, gene silencing

Language :: English
Database :: OpenAIRE
Journal :: CNS & neurological disorders. Drug targets 14 (2015): 168–175. doi:10.2174/1871527314666150116123305, info:cnr-pdr/source/autori:Cogoni C, Ruberti F, Barbato C/titolo:MicroRNA Landscape in Alzheimer's Disease./doi:10.2174%2F1871527314666150116123305/rivista:CNS & neurological disorders. Drug targets/anno:2015/pagina_da:168/pagina_a:175/intervallo_pagine:168–175/volume:14
Accession number :: edsair.pmid.dedup....3822a6eb864425797125b7639d1e201a
Full Text :: https://doi.org/10.2174/1871527314666150116123305