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IL12B polymorphism and type 1 diabetes in the Italian population: A case-control study
- Source :
- Scopus-Elsevier, Diabetes (N.Y.N.Y.) 51 (2002): 1649–1650., info:cnr-pdr/source/autori:Nisticò L., Giorgi G., Giordano M., Galgani A., Petrone A., D'Alfonso S., Federici M., Di Mario U., Pozzilli P., Buzzetti R. and Cascino I./titolo:IL12B polymorphism and type 1 diabetes in the Italian population: a case-control study/doi:/rivista:Diabetes (N.Y.N.Y.)/anno:2002/pagina_da:1649/pagina_a:1650/intervallo_pagine:1649–1650/volume:51
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Abstract
- A polymorphism in the interleukin 12B gene was recently reported to be strongly associated with type 1 diabetes in 422 Australian and British families. We analyzed the same polymorphism in 470 Italian type 1 diabetic patients and 544 matched control subjects and found no evidence of association with the disease.
- Subjects :
- onset age
Adult
Male
genetic epidemiology
Settore MED/09 - Medicina Interna
genetic association
Adolescent
phenotype
genotype
gene frequency
genetic risk
insulin dependent diabetes mellitus
Genetic
Risk Factors
Diabetes Mellitus
genetic polymorphism
Humans
controlled study
Genetic Predisposition to Disease
human
Polymorphism
Child
Polymorphism, Genetic
interleukin 12
allele
article
clinical feature
disease course
female
genetic predisposition
Italy
major clinical study
male
priority journal
risk assessment
school child
Case-Control Studies
Diabetes Mellitus, Type 1
Female
Gene Frequency
Haplotypes
Interleukin-12
Settore M-EDF/01 - Metodi e Didattiche delle Attivita' Motorie
Type 1
Subjects
Details
- Database :
- OpenAIRE
- Journal :
- Scopus-Elsevier, Diabetes (N.Y.N.Y.) 51 (2002): 1649–1650., info:cnr-pdr/source/autori:Nisticò L., Giorgi G., Giordano M., Galgani A., Petrone A., D'Alfonso S., Federici M., Di Mario U., Pozzilli P., Buzzetti R. and Cascino I./titolo:IL12B polymorphism and type 1 diabetes in the Italian population: a case-control study/doi:/rivista:Diabetes (N.Y.N.Y.)/anno:2002/pagina_da:1649/pagina_a:1650/intervallo_pagine:1649–1650/volume:51
- Accession number :
- edsair.pmid.dedup....18463e82f4f46e407b9326b9cb8ddf98