Lineage tracing of human development through somatic mutations

Authors :: Michael, Spencer Chapman
Anna Maria, Ranzoni
Brynelle, Myers
Nicholas, Williams
Tim H H, Coorens
Emily, Mitchell
Timothy, Butler
Kevin J, Dawson
Yvette, Hooks
Luiza, Moore
Jyoti, Nangalia
Philip S, Robinson
Kenichi, Yoshida
Elizabeth, Hook
Peter J, Campbell
Ana, Cvejic
Source :: Nature. 595(7865)
Publication Year :: 2020
Abstract: The ontogeny of the human haematopoietic system during fetal development has previously been characterized mainly through careful microscopic observations

Subjects :: Male
Blood Cells
Time Factors
Whole Genome Sequencing
Hematopoietic System
DNA Mutational Analysis
Embryonic Development
Clone Cells
Workflow
Mesoderm
Fetus
Mutation Rate
Health
Organ Specificity
Karyotyping
Mutation
Humans
Cell Lineage
Germ Layers

Tools