Distortion correction in diffusion-weighted imaging of the breast: Performance assessment of prospective, retrospective, and combined (prospective + retrospective) approaches

To compare the effectiveness of prospective, retrospective, and combined (prospective + retrospective) EPI distortion correction methods in bilateral breast diffusion-weighted imaging (DWI) scans.Five healthy female subjects underwent an axial bilateral breast DWI exam with and without prospective BThe average cross-correlation coefficient between the DWI images and the anatomical reference scan was increased from 0.82 to 0.92 over the five volunteers when combined prospective and retrospective distortion correction was applied. Furthermore, such correction substantially reduced patient-to-patient variation of the image alignment and the variability of the average apparent diffusion coefficient in normal glandular tissue.Combined prospective and retrospective distortion correction can provide an efficient way to reduce susceptibility-induced image distortions and enhance the reliability of breast DWI exams. Magn Reson Med 78:247-253, 2017. © 2016 International Society for Magnetic Resonance in Medicine.