Back to Search
Start Over
Exacerbations of Chronic Obstructive Pulmonary Disease Tool to assess the efficacy of acute treatment
- Source :
- International Journal of Chronic Obstructive Pulmonary Disease
- Publication Year :
- 2019
-
Abstract
- Background and objective The Exacerbations of Chronic Obstructive Pulmonary Disease Tool-Patient-Reported Outcomes (EXACT-PRO) has been suggested as a reliable and valid measure for early assessment of COPD exacerbations and perceived recovery. However, there has been no evidence for EXACT-PRO efficacy in assessing recovery from treatment in a randomized controlled trial. The study evaluated the reliability, validity, and responsiveness of EXACT-PRO for the evaluation of the efficacy of acute treatment in patients with COPD exacerbation. Methods In a Phase III randomized controlled study for assessing the efficacy of antibiotic treatment on COPD exacerbation, EXACT-PRO was evaluated in the responders and non-responders. Results A total of 295 patients were analyzed (259 responders and 37 non-responders). Cronbach’s α was 0.96 for EXACT total, 0.96 for the breathlessness domain, 0.89 for the cough and sputum domain, and 0.93 for the chest symptoms domain. The EXACT score correlated with the COPD assessment test (CAT) score (r=0.8, P
- Subjects :
- Male
PRO
Time Factors
Patient-Reported Outcomes
The Exacerbations of Chronic Obstructive Pulmonary Disease Tool
Pulmonary Disease, Chronic Obstructive
exacerbation
Double-Blind Method
Predictive Value of Tests
EXACT
Republic of Korea
Humans
COPD
Patient Reported Outcome Measures
Prospective Studies
Lung
Aged
Original Research
Sputum
Reproducibility of Results
Recovery of Function
Middle Aged
Anti-Bacterial Agents
Dyspnea
Treatment Outcome
Disease Progression
Female
Fluoroquinolones
Subjects
Details
- ISSN :
- 11782005
- Volume :
- 14
- Database :
- OpenAIRE
- Journal :
- International journal of chronic obstructive pulmonary disease
- Accession number :
- edsair.pmid..........fbad4805503eb10dbc1f66fd34c9cc88