Back to Search Start Over

A Nuclear RNA Degradation Pathway Helps Silence Polycomb/H3K27me3-Marked Loci in

Authors :
Anna, Mattout
Dimos, Gaidatzis
Véronique, Kalck
Susan M, Gasser
Source :
Cold Spring Harbor symposia on quantitative biology. 84
Publication Year :
2020

Abstract

In fission yeast and plants, RNA-processing pathways contribute to heterochromatin silencing, complementing well-characterized pathways of transcriptional repression. However, it was unclear whether this additional level of regulation occurs in metazoans. In a genetic screen, we uncovered a pathway of silencing in

Details

ISSN :
19434456
Volume :
84
Database :
OpenAIRE
Journal :
Cold Spring Harbor symposia on quantitative biology
Accession number :
edsair.pmid..........f5cf94369730488c2df1f1ed9e84cee1