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Assessment and Validation of Syndromic Case Definitions for Respiratory Syncytial Virus Testing in a Low Resource Population

Assessment and Validation of Syndromic Case Definitions for Respiratory Syncytial Virus Testing in a Low Resource Population

Authors :
Omer, Saad B.
Bednarczyk, Robert
Kazi, Momin
Guterman, L. Beryl
Aziz, Fatima
Allen, Kristen E.
Yildirim, Inci
Ali, S. Asad
Source :
The Pediatric Infectious Disease Journal
Publication Year :
2018
Publisher :
Williams & Wilkins, 2018.

Abstract

Supplemental Digital Content is available in the text.<br />Standardized case definitions are needed in decision-making regarding respiratory syncytial virus control strategies, including vaccine evaluation. A syndromic case definition comprising of “wheeze or apnea or cyanosis” could be useful for community-based surveillance of moderate respiratory syncytial virus infection among young infants particularly in resource-limited settings. However, this definition showed modest specificity (29.2%–49.6%), indicating that community-based surveillance may need augmentation with other data.

Details

Language :
English
ISSN :
15320987 and 08913668
Volume :
38
Issue :
3
Database :
OpenAIRE
Journal :
The Pediatric Infectious Disease Journal
Accession number :
edsair.pmid..........f480d2cd3904158e1c73063a9d26baff