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[The Present Status of Surgical and Endoscopic Treatment for Gastric Cancer Patients Aged 85 Years or Older]

Authors :
Nobuhiro, Takiguchi
Yoshihiro, Nabeya
Reiri, Shimazaki
Atsushi, Ikeda
Hiroaki, Soda
Toru, Tonooka
Osamu, Kainuma
Shunsuke, Imanishi
Hidehito, Arimitsu
Ryosuke, Kobayashi
Tomofumi, Chibana
Fumitaka, Ishige
Hiroshi, Yamamoto
Matsuo, Nagata
Takuto, Suzuki
Source :
Gan to kagaku ryoho. Cancerchemotherapy. 43(12)
Publication Year :
2017

Abstract

This study aimed to survey treatment ofgastric cancer via gastrectomy or endoscopic submucosal dissection(ESD)in patients aged 85 years or older and to clarify the risks and benefits of gastrectomy in terms of postoperative complications and prognosis. The analysis included 40 patients who were treated via gastrectomy and 41 who were treated via ESD. All patients were aged 85 years or older. Although most ofthe patients who had gastrectomy had good performance status(PS), comorbidities were found in 72.5%, and limited operation was often performed. In the gastrectomy group, R0 tumor-free resection margins were achieved in 75%, and postoperative complications occurred in 45%. Despite R0 surgery, the 2-year overall survival rate was 61.7% and the 3-year overall survival was 42.9%. Seven patients(17.1%)in the ESD group were diagnosed with T1b tumors, and no patients were shifted to surgery. Treatment decisions for super-elderly gastric cancer patients are made with regard to age, PS, and comorbidities. There is a limit to survival time after radical gastrectomy. It is necessary to examine the negative effect of gastrectomy on survival time. Selected patients aged 85 years or older with T1b gastric cancer should be given the option of ESD.

Details

ISSN :
03850684
Volume :
43
Issue :
12
Database :
OpenAIRE
Journal :
Gan to kagaku ryoho. Cancerchemotherapy
Accession number :
edsair.pmid..........f0cdc3b847cf3929f562e73d43e71e19