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One-year clinical outcome of elderly patients undergoing angioplasty for ST-elevation myocardial infarction complicated by cardiogenic shock: the importance of 3-vessel disease and final TIMI-3 flow grade
- Source :
- The Journal of invasive cardiology. 26(3)
- Publication Year :
- 2014
-
Abstract
- The influence of age on clinical results of primary percutaneous coronary intervention (PCI) in patients with ST-elevation myocardial infarctions (STEMI) complicated by cardiogenic shock (CS) is poorly investigated.In this study, we evaluated the outcome of 216 consecutive all-comer patients with STEMI and CS undergoing PCI who were divided into 2 groups according to age:75 years (n = 131) or ≥75 years (n = 81). The study endpoint was the incidence of death at 1-year follow-up. The predictors of mortality at 1 year were also investigated.The group75 years had a significantly lower incidence of death compared with the group ≥75 years at 30 days (39% vs 69%; P=.01) and 1 year (51% vs 79%; P.001). Cox proportional hazards model identified: age (adjusted hazard ratio [HR] = 1.02; 95% confidence interval [CI], 1.00-1.03; P=.02), 3-vessel disease (HR = 1.47; 95% CI, 1.00-2.17; P=.05), post-PCI TIMI flow grade 0-1 (HR = 2.48; 95% CI, 1.66-3.70; P=.01) and grade 2 (HR = 1.68; 95% CI, 1.01-2.80; P=.05) after PCI as independent predictors of death at 1-year follow-up.Patients ≥75 years with STEMI complicated by CS and treated by PCI have higher 1-year mortality compared with younger counterparts. Final TIMI 0-2 and 3-vessel disease are strong predictors of death. This finding may be valuable in risk stratification of these patients.
- Subjects :
- Adult
Aged, 80 and over
Male
Endpoint Determination
Age Factors
Myocardial Infarction
Shock, Cardiogenic
Middle Aged
Prognosis
Risk Assessment
Survival Rate
Electrocardiography
Percutaneous Coronary Intervention
Treatment Outcome
Humans
Female
Aged
Follow-Up Studies
Proportional Hazards Models
Retrospective Studies
Subjects
Details
- ISSN :
- 15572501
- Volume :
- 26
- Issue :
- 3
- Database :
- OpenAIRE
- Journal :
- The Journal of invasive cardiology
- Accession number :
- edsair.pmid..........f07a7b4e48f03e0ef58817de2df1e002