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[The role of the hypophysis and STH in the regulation of the androgenic receptor level of the rat liver and in the realization of the sex-differentiating action of gonadal hormones]

Authors :
N V, Oleĭnik
O V, Smirnova
V B, Rozen
Source :
Problemy endokrinologii. 36(5)
Publication Year :
1990

Abstract

The role of the pituitary gland was investigated in the regulation of the level of rat liver androgenic receptors (AR) and in the realization of polydifferentiating action of gonadal hormones. The level of AR in the female and male rat liver was shown not to depend directly on the presence of the pituitary gland or STH administration. The pituitary gland is not a mediator in the realization of polydifferentiating action of androgens and estrogens. STH enhances the development of a positive effect of androgens on the level of AR.

Details

ISSN :
03759660
Volume :
36
Issue :
5
Database :
OpenAIRE
Journal :
Problemy endokrinologii
Accession number :
edsair.pmid..........f012d42a20f2dfac0b35c9a1b4f86c47