Synthesis and Pharmacological Evaluation of New

Authors :: Paloma, Narros-Fernández
Mourad, Chioua
Sonia A, Petcu
Daniel, Diez-Iriepa
Laura, Cerrada-Gálvez
Céline, Decouty-Pérez
Alejandra, Palomino-Antolín
Eva, Ramos
Víctor, Farré-Alins
Ana Belén, López-Rodríguez
Alejandro, Romero
José, Marco-Contelles
Javier, Egea
Source :: Journal of medicinal chemistry. 65(8)
Publication Year :: 2022
Abstract: NLRP3 is involved in the pathophysiology of several inflammatory diseases. Therefore, there is high current interest in the clinical development of new NLRP3 inflammasome small inhibitors to treat these diseases. Novel

Subjects :: Mice, Inbred C57BL
Mice
Gout
Hyperalgesia
Inflammasomes
Interleukin-1beta
NLR Family, Pyrin Domain-Containing 3 Protein
Anti-Inflammatory Agents
Animals

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